Innovation

Vaccines: Our history, our legacy

MSD and its legacy companies have been working to discover and develop vaccines for more than a century

May 8, 2024

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“An epidemic of diphtheria is almost inevitable here. Stop. I am in urgent need of one million units of diphtheria antitoxin. Stop. Mail is only form of transportation. Stop.”

  • Dr. Curtis Welch

This was the desperate radio telegram in January 1925 from Dr. Curtis Welch in Nome, Alaska, to all the major Alaska towns, to territorial governor Scott Bone in Juneau, and to the U.S. Public Health Service in Washington, D.C. Diphtheria was spreading through the icebound community. Children had already died, and the local supply of diphtheria antitoxin had expired the previous summer.

Known as the “Great Race of Mercy,” it’s an iconic story of human compassion.

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Weather prevented delivery by air, so relay teams of sled dogs and their mushers raced against the clock to deliver 300,000 units of antitoxin, which was produced by MSD legacy company H.K. Mulford. They completed the 674-mile journey over what later became known as the Iditarod Trail in a record-breaking five days and seven hours despite whiteout conditions and temperatures of 50 degrees below zero.

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Over 130 years of vaccine leadership

In 1895, the H.K. Mulford Company began marketing the first commercially available diphtheria antitoxin in the U.S., the very medication that helped avert the diphtheria epidemic in Nome. Today, we have a significant presence in vaccine discovery, development and distribution in both human and animal health.

Dr. Maurice Hilleman

The vaccine pioneers

MSD’s Dr. Maurice Hilleman belongs to a distinguished group of vaccine pioneers — including Edward Jenner, Louis Pasteur, Jonas Salk and Albert Sabin. Hilleman is credited with helping to develop more than 40 vaccines and his impact on public health is undeniable.