Sustainability

MSD publishes Impact Report 2022/2023

Letter from our chairman and chief executive officer, Rob Davis

August 9, 2023

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Dear Stakeholders,

Thank you for your interest in MSD and our ongoing commitment to operating responsibly and creating value for patients, our stakeholders and our business. We continue to take inspiration from our purpose and our unique opportunity to use the power of leading-edge science to save and improve lives around the world.

Sustainable value creation is core to how we do business as we work to advance global health, apply innovative science and ultimately protect and improve the health of people and animals through the development and delivery of medicines, vaccines and technology solutions. We’re passionate about this work and committed to making a positive difference for patients and the world while driving strong business outcomes. Working globally as One Team, we organize our sustainability efforts across four focus areas to create long-term value: 1) expanding access to health; 2) developing and rewarding a diverse, inclusive and healthy workforce; 3) protecting the environment; and 4) operating with the highest standards of ethics and values.

Expanding access to health

Two years ago, we set a goal to enable 100 million more people to access our innovative portfolio globally, through access strategies, solutions and partnerships, by 2025. We exceeded this goal already in 2022. As a result, we increased our ambition and more than tripled our original goal. We now aim to enable 350 million more people to access our innovative portfolio by 2025.

We’re eager to reach more people not only now, but in the years to come. To this end, we pursued new scientific discoveries with an investment last year of $13.5 billion in research and development. In total, our products and pipeline seek to address 83% of the top 20 global burdens of diseases.

In 2022, our MECTIZAN® Donation Program turned 35 years old. The longest-running disease-specific drug donation program of its kind, this successful effort to combat river blindness and lymphatic filariasis reached nearly 360 million people last year1. We also invested $38 million to advance health equity through initiatives like MSD for Mothers. These investments support our goal to reach over 30 million people in low- and middle-income countries (LMICs) and in U.S. underserved populations with our social investments, by 2025. We surpassed this goal as well in 2022. Our new goal is to reach over 50 million people in LMICs, underserved populations in the U.S. and, going forward, underserved populations in other high-income countries, by 2025.

Developing and rewarding a diverse, inclusive and healthy workforce

We’re committed to investing in our colleagues and building a strong pipeline of talent as an employer of choice. Across our organization, we value diversity and inclusion as both an ethical and business priority.

We’re becoming even more inclusive in our hiring, working with organizations including OneTen, a business coalition striving to close the opportunity gap for Black workers without four-year college degrees. In order to create more access to meaningful career opportunities for diverse candidates, we posted about 900 job openings not requiring a four-year degree, which was twice as many as the previous year. In addition, in 2022 we hosted 90 student interns through Year Up, a nonprofit serving economically disadvantaged young people. Women represented more than half of our new hires globally, and in the U.S., 47% of new hires came from underrepresented ethnic groups.

We have a longstanding commitment to fair and equitable pay for all employees doing similar work. In the U.S., our 2022 study found that we had achieved greater than 99% pay equity for female and male employees, as well as non-white (including Black, Hispanic and Asian employees) and white employees. Our commitment to diversity and inclusion also extends to our business partners. Last year, we spent $3.2 billion with diverse Tier 1 and 2 suppliers globally.

Protecting the environment

Our company has a long history of environmental stewardship, and we believe a healthy planet is essential to improving health and protecting the sustainability of our business. As part of this work, we have committed to the Science Based Targets initiative (SBTi) to set a net-zero target for our greenhouse gas (GHG) emissions across our global operations (Scopes 1, 2, 3).

We know that each of our research, production and office facilities plays a role in achieving our goals for energy efficiency, waste reduction and overall sustainability. In 2022, we created a Waste Diversion Playbook to help sites contribute to our goals through local waste-diversion strategies, such as composting and recycling, and environmentally responsible procurement practices.

Operating with the highest standards of ethics and values

We operate responsibly every day, holding ourselves to the highest standards of ethics and values. Our code of conduct defines our corporate character and helps us protect our reputation as a trustworthy company. We maintain 100% compliance to regulatory requirements for active incident monitoring, risk and harm analysis, and timely notification of data breaches. We also encourage employees to speak up and report potential concerns, ensuring our ethics and values are reflected in all we do.

As a signatory to the United Nations Global Compact (UNGC), MSD remains committed to improving our communities through our operations, aligning our efforts with the Ten Principles of the UNGC.

In late 2021, we announced the issuance of our first $1 billion sustainability bond to support initiatives and partnerships contributing to the advancement of the United Nations Sustainable Development Goals. Through June 2022, we allocated $760 million of the net proceeds toward social and green projects, in alignment with our sustainability financing framework.

While my colleagues and I are pleased by our 2022 progress, we remain committed to doing more to advance and protect the health of our employees, communities and planet. Indeed, I want to thank our colleagues and partners for the passion and expertise brought to this work every day. I’m honored to work alongside such a talented and dedicated team.

Thank you again for your interest in our company’s progress and performance. We’re excited for our future — and the unique opportunity we have to make a difference through our research, our medicines and vaccines, and our enduring commitment to sustainable innovation and value creation.

Very best regards,

Rob Davis

Chairman & Chief Executive Officer

1 Countries receiving donated Mectizan are located in Africa, Asia, the Middle East, South America, and the Western Pacific

Innovation

Our Q2 2023 earnings report

August 1, 2023

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MSD’s Q2 2023 results reflect sustained underlying growth. Our company announced Q2 worldwide sales of $15.0 billion, an increase of 3% from Q2 2022.

“We continue to make great progress as we advance our broad and deep pipeline, raise the bar of innovation, and bring forward leading-edge science to save and improve lives around the world,” said Rob Davis, chairman and chief executive officer, MSD. “We delivered robust underlying growth during the second quarter and are well positioned to achieve strong full-year results. I’m proud of our talented, diverse and dedicated global team that continues to focus on creating value for patients and all our stakeholders now and well into the future.”

MSD anticipates full-year 2023 worldwide sales to be between $58.6 billion and $59.6 billion.

Take a look at the infographic below for more details on Q2 2023 results.

Download infographic

MSD Q2 2023 Earnings Infographic
Our people

Meet two women at the forefront of our HIV research

Two esteemed scientists share their motivations and hopes for the future of HIV research

July 19, 2023

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The field of HIV research has changed drastically in the past 40 years. In that time, we’ve evolved from helping people with HIV struggle to survive to seeing them fully thrive. Now we’re chasing a cure for HIV.

On top of a shift in focus, we’ve also seen a transformation in those who occupy the research space: more and more women are joining the fight.

We spoke with two of our own researchers who are leading the charge, Bonnie Howell, Ph.D., and Rebeca Plank, M.D., about what drives them, what’s changed, and what’s next in the HIV research landscape.

What drew you to HIV research?

Rebeca Plank: I think my interest was first sparked at home by my parents, who actually met doing public health work in Chile. But it’s funny, despite that background, I wasn’t pre-med in college. I was an anthropology major. But during my senior thesis, I worked on a project around HIV prevention messaging. That stuck with me.

Quote from Rebeca Plank "I was inspired to pursue science and population health where I continuously ask the question, 'How can we make it easier for people to improve their health?'"

This includes making interventions relevant and accessible.

Bonnie Howell: I can relate to that. I started working in HIV research after years of working in oncology and quickly recognized the unmet medical need. I realized that a lot of what I learned about cancer research could be applied to HIV as well.

I became passionate about HIV research because I saw it as an opportunity to change the storyline and apply my oncology experience to this different field.

In your mind, what’s been the biggest shift in HIV care?

RP: I think the vast shift can be summed up by what I saw in med school. I was studying in San Francisco between 1996–2001, and I watched an inpatient hospital ward go from a place that housed critically ill people to a general medicine ward full of people rightfully expecting to feel better and go back home.

And that’s all due to the fast and impactful medical innovations — such as antiretrovirals to treat HIV — that helped save so many lives.

In a field that’s been historically male dominated, how does it feel to be a female in science and HIV research?

BH: My experience is definitely unique because I’ve been at MSD for my entire career — and I’ve been constantly surrounded by powerful and brilliant women. It’s been a privilege to be a part of a company that champions diversity and inclusion and has empowered me to roll up my sleeves and contribute day in and day out to this important mission.

And I’m grateful for the chance to continue to add to the legacy MSD has established for itself in HIV — helping to change the way HIV has been treated since the start of the epidemic.

RP: That said, there are still challenges facing women in HIV research. As a med student and also as a resident, it struck me that, looking around the hospital, there were relatively few women who were further along in their careers. It can be so important to see people succeeding who look like you, as role models and mentors — they show you what’s possible.

BH: I completely agree. I also count myself lucky that I was mentored by female leaders who charted the course and were instrumental in increasing the number of women in research. Now I pay that forward and mentor the next generation of female researchers — especially those pursuing HIV.

Why do you think gender diversity is critical in HIV research?

BH: Globally, women bear a huge brunt of this epidemic. A study in 2021 showed that 54% of all people with HIV are women and girls. Yet women are significantly under-represented in HIV clinical trials. We need to change that.

Equally important is making sure that the female perspective is represented within the HIV research community, so women with HIV can have advocates who share and understand their unique female experiences.

RP: Prior to joining MSD, during my time doing field work in Kenya and Botswana, I learned a lot about the nuances and unique hardships of the female HIV experience. Globally, advocating for herself may not always be a woman’s first priority. Not to mention that the stigma of HIV is still too prevalent around the world, which may make it harder to seek care.

Quote from Bonnie Howell "It's so important to be a woman in HIV research. My goal is to represent women with HIV and be their voice and champoin."

What advancement in HIV research do you hope to see during your lifetimes?

BH: A cure. Whether that’s eradicating HIV from patients’ bodies or remission, where the virus still exists in the body but is controlled without lifelong treatment.

RP: And then getting this cure — as well as other treatments and better methods for HIV prevention — to people in need, in the manner they need it. Access remains a huge issue, and part of that is the mode of treatment such as frequency of pills or injections. We hear consistently that having discreet treatment and prevention options would be critical.

What gives you the most hope?

RP: So much can evolve in a single generation. These young women we’re working to help, someday they’ll be grandmothers. By empowering them with knowledge and by continuing our work in HIV, we hope to protect future generations.

BH: The HIV community is so passionate and engaged, and we’re designing studies and treatments with those affected in mind. I’m excited to see what the future brings.

Innovation

Researching new uses for a therapy that targets cancer cells

MSD scientists are evaluating potential antibody-drug conjugate (ADC) targets across both blood cancers and solid tumors

July 17, 2023

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More than two decades since the first approval of an antibody-drug conjugate (ADC), a therapy with the ability to target specific cancer cells, scientists continue to explore new opportunities for helping patients.

What are antibody-drug conjugates (ADCs)?

ADCs are a targeted means to deliver chemotherapy. Unlike conventional chemotherapy treatments, ADCs are designed to deliver chemotherapy to a specific target expressed on the surface of cancer cells. After binding to the target, the ADC is designed to release an agent that is toxic to cancer cells.

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“With ADCs, the antibody provides the targeting mechanism, like a zip code directing the delivery of the chemotherapy agent to the cancer cells."

Dr. David Weinstock

Vice president of discovery oncology at MSD Research Laboratories

Scientists, including our own, are researching new opportunities with ADCs. “The learnings we’ve seen in ADCs over the last few years are very encouraging. And certainly, we should expect to see more of that research in the coming years,” said Weinstock.

MSD scientists are evaluating a number of potential ADC targets across both blood cancers and solid tumors, including ROR1, TROP-2 and others in the preclinical space.

  • ROR1 is a protein expressed mainly on blood and solid tumor cells, but not in normal adult cells. It’s associated with more aggressive disease that does not respond to current therapies. We’re evaluating a ROR1 targeting ADC in patients with mantle cell lymphoma or diffuse large B-cell lymphoma along with solid tumors.
  • TROP-2 is overexpressed in many cancers including triple-negative breast cancer and lung cancer. High levels of TROP-2 expression are associated with cancer cell growth, correlating with more aggressive forms of disease.

By evaluating a number of ADC targets, we hope to contribute important new research exploring the potential of ADCs and advance our purpose to use the power of leading-edge science to save and improve lives around the world.

Innovation

Podcast: Why neuroscience is the ‘final frontier’

Listen as specialists from MSD discuss what they’re most excited about in researching potential treatments for neurologic disorders

July 13, 2023

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Our scientists are revolutionizing how we discover and develop treatments to address unmet medical needs in a number of areas, including neuroscience.

“It’s sort of like the final frontier,” said Joe Herring, scientific AVP, clinical research, in our new podcast. “You’re going off into space to try to figure out how to do very difficult things.”

For more, listen in as Herring sits down with MSD clinical research team senior principal scientists Yuki Mukai and Ari Merola as well as business development director Paige Lacatena to explore today’s breakthroughs and challenges in the field of neuroscience.

Listen to the podcast

Read the full transcript

Explore careers in R&D at MSD

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Careers

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Innovation

Welcome home: Celebrating our new global headquarters

Take a look inside our state-of-the-art reimagined workplace

July 3, 2023

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Colleagues across our company celebrated our “homecoming” and ushered in a new era of collaboration for patients around the world with a ribbon-cutting at our global headquarters in Rahway, New Jersey, in June.  

Rahway was the site of our first manufacturing plant, and was our former headquarters from 1926 to 1992. The updated collaborative workspace brings together all of our divisions and leadership teams in one location.  

“When you think about what it takes to ideate, to innovate, to invent — it takes collaboration, it takes teamwork, it takes all of us focused on what matters most, which is putting the patient at the center of everything we do and delivering with urgency on their behalf,” Chairman and CEO Rob Davis said. “And we’re now able to do that as one unified company at this facility.”

Health awareness

LGBTQ+: Starting a conversation with a health care provider

Dr. Alix Casler suggests ways for LGBTQ+ individuals to find supportive care

June 20, 2023

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For LGBTQ+ patients, it can be difficult to share and discuss your sexual orientation and gender identity with a health care professional, but there are some details they might need to know.   

Dr. Alix Casler — a pediatrician, director of medical affairs, and mother of three children who are members of the LGBTQ+ community — shared her insights to help guide conversations with a health care provider for people who might not know where to begin.  

Finding a safe, accepting space for LGBTQ+ care 

Casler, also a member of our Rainbow Alliance Employee Business Resource Group (EBRG), suggests doing some research and making sure it’s a good fit before deciding on a health care provider.  

“There’s no easy way to gauge a doctor’s familiarity with LGBTQ+ care, but one way to find a safe, accepting space in your community is to look for pride flags or ribbons,” Casler said. “Providers sometimes might wear rainbow ribbons on their badges to let you know they’re either members of the community or allies. However, it’s not always that easy, and patients may need to do their own research to find a supportive provider.” 

Casler said it’s vital to be 100% transparent with a trusted health care provider because the people treating you should know as much as they can to help give the best care possible.  

“This is the person who’s responsible for helping you take care of your physical and mental health in an individualized, personal way,” Casler said. Someone might be wondering, ‘Should I come out to my doctor?’

"You owe it to yourself to find a provider that you're comfortable asking anything and telling everything. There's no question that's inappropriate for you to ask in choosing the right provider for you."

–Dr. Alix Casler

Well-being involves mental health, too 

Caring for your mental health is so important.

“Some people in the LGBTQ+ community could be facing mental health issues due to fear of rejection, fear of violence or fear of being exposed when they’re not ready to be exposed,” Casler said. “When you’re not ready to be open, just the stress of covering up who you are could lead to depression or anxiety.”  

Casler said finding a mental health counselor who understands the stresses associated with covering and importance of psychological safety is paramount for LGBTQ+ individuals’ mental health care. 

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“I always want to help families understand a little bit more and help parents become allies and advocates for their kids.”

–Dr. Casler

“Resources are available and can be identified through trusted organizations in your local community or nationally through non-profits or public health agencies to make the right decision regarding your health.” 

How MSD supports the LGBTQ+ community 

While there has been great progress when it comes to LGBTQ+ rights, there’s still work to be done — and our company is proud to play a role in achieving those goals.  

Innovation

Here for Good: Harnessing innovation to reach indigenous communities

We’re hunting for new ways to increase patient access, including using drones to deliver medicines to remote communities

June 16, 2023

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Alaska is a vast state with extremes in weather and terrain. For people living in its 240 remote villages and communities, obtaining lifesaving medicines can be a challenge. And extreme challenges call for innovative solutions.

To help, we teamed up with the University of Alaska, a drone provider, local governments and others to demonstrate the use of drones to increase access to medicines in a proof-of-concept project. The drone was outfitted with thermal protection system packaging for the safe delivery of temperature-sensitive pharmaceuticals.

Drone technology expands access to medicines where it’s needed most

For our colleague and drone project adviser Leslie Brunette, this is the culmination of work that began more than a decade ago in her hometown of Fargo, North Dakota.

“I was introduced to a young man from a tribal community, and his grandmother had invited me to go and visit him,” said Brunette, who also serves as the global lead for MSD’s Native American and Global Indigenous People employee business resource group. She explained that the young man suffered from a chronic illness, and the remote location of his community meant a trek of two to three hours to be able to access health care. A few years later, he became sick and had to be moved off of the reservation to receive care.

“When he passed away, because of how much we learned about his family and his culture, I knew that more needed to be said and needed to be done. So I made that commitment to continue to try and be a voice that raised and elevated the awareness of indigenous communities across the United States and the world.”

From dog sleds to drone delivery

It’s not the first time we’ve found an innovative way to deliver health care to families in Alaska. The annual Iditarod race commemorates a 1925 sled dog team relay that brought an antitoxin produced by MSD legacy company H.K. Mulford to Nome through blizzard conditions to help fight a deadly epidemic.

We’re proud of our company’s long history of expanding access to medicines and vaccines and working with our partners to create innovative solutions to help people in need.

Our people

A colleague enlists artist’s help to make peace with her diagnosis

Giving her brain tumor a name helped Gabriela Chiummo face her new reality

June 8, 2023

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Gabriela Chiummo has learned that sometimes terrible news can lead to the greatest joys in life.

As a senior specialist of regulatory affairs for our company’s Animal Health team, Chiummo moved almost 6,000 miles from her home in Brazil to Germany in 2018 for work. Soon after, she began experiencing consistent headaches. One day while out grocery shopping, she lost her sight.

It only lasted a few seconds, but it was enough to send her to the doctor.

A surprising diagnosis

Chiummo compares her first experience in an MRI machine to meditating. She was calm, almost soothed before she was given the news: she has a meningioma, a type of brain tumor.

“I wasn’t sure how to react. In movies they show people hearing this kind of news and the words being spoken stop making sense – that’s what happened to me.”

“The world just stopped, and I was in complete shock. I went to the appointment alone, obviously not expecting this outcome. I didn’t know if I should call my husband, cry or contact my mom in Brazil. I had to carry on with this information, but it felt like I was living in a daze.”

To help face her new reality, Chiummo decided to do something unconventional, but very personal.

“I decided that I wanted to name my tumor because I name everything,” Chiummo said. “My house has a name, my car has a name, everything, so I decided I should name my tumor too since it’s here. It’s living with me, and we need to communicate, we need to communicate well, since it’s going to be there not paying rent. I need to make the most of it.”

She named her tumor Rosângela.

She even took it a step further, and an artist living in Brazil, Julia Larotonda, helped bring Rosângela to life as a cartoon character. This enabled Chiummo to visualize and get to know her new, unwanted guest. Rosângela has glasses and wears her hair in a side ponytail, just like Chiummo.

Endless support from friends and family

Once she finally told her friends and family about the news, she was warmed by the outpouring of love and compassion she received.

“Everybody was so amazing,” Chiummo said. “I received so much love, so much kindness. Everyone was offering help in some way, by either visiting my mother to comfort her or being there to help support me. I was most surprised when my colleagues in Germany even offered to attend doctors’ appointments with me to help translate, in case there was a language barrier.”

She said so many people were willing to help, that it really put life into perspective.

Gabriella Chiummo

“People think that I’m crazy – but I think I’ve never been happier in my entire life. It’s like I’m really able to focus on the good parts, and no matter how bad it gets, I’m so lucky to be surrounded by this support and love.”

  • Gabriela Chiummo

As she continues to meet with doctors, learns more about her tumor, Rosângela, and determines next steps, Chiummo says it’s easiest to take it a day at a time.

“I cannot control what’s happening, so I have to live in the present moment,” she said.

Using her new outlook to inspire colleagues and friends

Chiummo said the news of Rosângela changed her perspective on life, and she wants to share her story to help others dealing with similar situations.

Chiummo has been part of several of our company’s employee business resource groups (EBRG) to connect with colleagues around the world. Now, the connections feel more personal.

“I had the chance to participate in a mentoring program, and it was amazing,” she said. “Everyone is connected in some way, and I’ve been able to meet wonderful people who I can share my story with and potentially spark some inspiration to continue working toward creating life-saving medicines. How can I possibly complain about the life I’ve been given?”

Our people

Podcast: Meet the dealmakers 

MSD’s business development and licensing team explain how they identify new opportunities to strengthen our robust R&D pipeline  

June 5, 2023

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It takes a special kind of talent to find and secure the right deals to keep us at the forefront of innovation. Leaders from our business development and licensing team sat down to discuss how their work is a key component to building and maintaining a strong pipeline.  

Here’s what you need to know:  

01.

Harnessing our legacy

Our reputation for using leading-edge science can make business development connections easier, explains Lizabeth Leveille, vice president, business development.


02.

The speed and determination to get it done

Elizabeth Naldi-Jacob, vice president, business development, knows that having a direct line of reporting to the top is what sets MSD apart as a potential partner. 


03.

Balancing the internal and the external  

We have a one pipeline mindset, and each asset receives the same focus and rigor whether it comes from inside our company or out, says Christopher Mortko, vice president, business development. 


04.

Working hand-in-hand with our scientists  

Grace Han McMahon, associate vice president, business development, explains why engaging our internal science leaders is crucial to making the right deals. 


05.

What we’re interested in (and why it’s everything) 

Our panelists discuss why we focus on five key areas — and when we’re willing to look beyond them.


Great partnerships begin with great conversation. Learn more about how discovery & development and licensing shape the future of MSD.  

For more, check out the full podcast: 

MSD BD&L

Read the transcript